Comparison of the transmembrane mucins MUC1 and MUC16 in epithelial barrier function.

Membrane-anchored mucins are present in the apical surface glycocalyx of mucosal epithelial cells, each mucosal epithelium having at least two of the mucins. The mucins have been ascribed barrier functions, but direct comparisons of their functions within the same epithelium have not been done. In a...

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Bibliographic Details
Main Authors: Ilene K Gipson, Sandra Spurr-Michaud, Ann Tisdale, Balaraj B Menon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4072602?pdf=render