Potential value of PTEN in predicting cetuximab response in colorectal cancer: An exploratory study

Potential value of PTEN in predicting cetuximab response in colorectal cancer: An exploratory study

<p>Abstract</p> <p>Background</p> <p>The epidermal growth factor receptor (EGFR) is over-expressed in 70–75% of colorectal adenocarcinomas (CRC). The anti-EGFR monoclonal antibody cetuximab has been approved for the treatment of metastatic CRC, however tumor response to...

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Main Authors: Koukouma Alona, Gikonti Ioanna, Galanidi Eleni, Bai Maria, Bobos Mattheos, Xanthakis Ioannis, Samantas Epaminontas, Kostopoulos Ioannis, Papamichael Dimitrios, Skarlos Dimosthenis V, Vrettou Eleni, Briasoulis Evangelos, Razis Evangelia, Kafiri Georgia, Papakostas Pavlos, Kalogeras Konstantine T, Kosmidis Paris, Fountzilas George
Format: Article
Language:English
Published: BMC 2008-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/234

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