Active Fraction from Embryo Fish Extracts Induces Reversion of the Malignant Invasive Phenotype in Breast Cancer through Down-Regulation of TCTP and Modulation of E-cadherin/β-catenin Pathway

Active Fraction from Embryo Fish Extracts Induces Reversion of the Malignant Invasive Phenotype in Breast Cancer through Down-Regulation of TCTP and Modulation of E-cadherin/β-catenin Pathway

Some yet unidentified factors released by both oocyte and embryonic microenvironments demonstrated to be non-permissive for tumor development and display the remarkable ability to foster cell/tissue reprogramming, thus ultimately reversing the malignant phenotype. In the present study we observed ho...

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Bibliographic Details
Main Authors: Sara Proietti, Alessandra Cucina, Andrea Pensotti, Pier Mario Biava, Mirko Minini, Noemi Monti, Angela Catizone, Giulia Ricci, Erica Leonetti, Abdel Halim Harrath, Saleh H. Alwasel, Mariano Bizzarri
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
tumor reversion
TCTP
embryo fish extract
cytoskeleton
E-cadherin/β-catenin
p53
Online Access:https://www.mdpi.com/1422-0067/20/9/2151

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