Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients

Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients

Sentinel lymph node biopsy (SLNB) emerged in the 1990s as a new technique in the surgical management of the axilla for patients with early breast cancer, resulting in lower complication rates and better quality of life than axillary lymph node dissection (ALND). Today SLNB is firmly established in t...

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Main Authors: Hazem Assi, Eman Sbaity, Mahmoud Abdelsalam, Ali Shamseddine
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/405949
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spelling doaj-abd3a58b1922467c9bb5e79f98a08e322020-11-24T23:04:16ZengHindawi LimitedBioMed Research International2314-61332314-61412015-01-01201510.1155/2015/405949405949Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer PatientsHazem Assi0Eman Sbaity1Mahmoud Abdelsalam2Ali Shamseddine3Department of Internal Medicine, American University of Beirut Medical Center, Cairo Street, P.O. Box 11-0236, Riad El Solh, Beirut 1107 2020, LebanonDepartment of Surgery, American University of Beirut Medical Center, Cairo Street, P.O. Box 11-0236, Riad El Solh, Beirut 1107 2020, LebanonDepartment of Medicine, Dalhousie University, 6299 South Street, Halifax, NS, B3H 4R2, CanadaDepartment of Internal Medicine, American University of Beirut Medical Center, Cairo Street, P.O. Box 11-0236, Riad El Solh, Beirut 1107 2020, LebanonSentinel lymph node biopsy (SLNB) emerged in the 1990s as a new technique in the surgical management of the axilla for patients with early breast cancer, resulting in lower complication rates and better quality of life than axillary lymph node dissection (ALND). Today SLNB is firmly established in the armamentarium of clinicians treating breast cancer, but several questions remain. The goal of this paper is to review recent work addressing 4 questions that have been the subject of debate in the use of SLNB in the past few years: (a) What is the implication of finding micrometastases in the sentinel nodes? (b) Is ALND necessary in all patients who have a positive SLNB? (c) How accurate is SLNB after neoadjuvant therapy? (d) Can SLNB be used to stage the axilla in locally recurrent breast cancer following breast surgery with or without prior axillary surgery?http://dx.doi.org/10.1155/2015/405949
collection DOAJ
language English
format Article
sources DOAJ
author Hazem Assi
Eman Sbaity
Mahmoud Abdelsalam
Ali Shamseddine
spellingShingle Hazem Assi
Eman Sbaity
Mahmoud Abdelsalam
Ali Shamseddine
Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients
BioMed Research International
author_facet Hazem Assi
Eman Sbaity
Mahmoud Abdelsalam
Ali Shamseddine
author_sort Hazem Assi
title Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients
title_short Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients
title_full Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients
title_fullStr Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients
title_full_unstemmed Controversial Indications for Sentinel Lymph Node Biopsy in Breast Cancer Patients
title_sort controversial indications for sentinel lymph node biopsy in breast cancer patients
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2015-01-01
description Sentinel lymph node biopsy (SLNB) emerged in the 1990s as a new technique in the surgical management of the axilla for patients with early breast cancer, resulting in lower complication rates and better quality of life than axillary lymph node dissection (ALND). Today SLNB is firmly established in the armamentarium of clinicians treating breast cancer, but several questions remain. The goal of this paper is to review recent work addressing 4 questions that have been the subject of debate in the use of SLNB in the past few years: (a) What is the implication of finding micrometastases in the sentinel nodes? (b) Is ALND necessary in all patients who have a positive SLNB? (c) How accurate is SLNB after neoadjuvant therapy? (d) Can SLNB be used to stage the axilla in locally recurrent breast cancer following breast surgery with or without prior axillary surgery?
url http://dx.doi.org/10.1155/2015/405949
work_keys_str_mv AT hazemassi controversialindicationsforsentinellymphnodebiopsyinbreastcancerpatients
AT emansbaity controversialindicationsforsentinellymphnodebiopsyinbreastcancerpatients
AT mahmoudabdelsalam controversialindicationsforsentinellymphnodebiopsyinbreastcancerpatients
AT alishamseddine controversialindicationsforsentinellymphnodebiopsyinbreastcancerpatients
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