Soft X-ray Laser Microscopy of Lipid Rafts towards GPCR-Based Drug Discovery Using Time-Resolved FRET Spectroscopy

Soft X-ray Laser Microscopy of Lipid Rafts towards GPCR-Based Drug Discovery Using Time-Resolved FRET Spectroscopy

Many signaling molecules involved in G protein-mediated signal transduction, which are present in the lipid rafts and believed to be controlled spatially and temporally, influence the potency and efficacy of neurotransmitter receptors and transporters. This has focus interest on lipid rafts and the...

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Bibliographic Details
Main Authors: Tatsuhiko Kodama, Shin Yoneya, Hiroto Kuroda, Motoyoshi Baba, Kazuyuki Masuda, Takao Hamakubo, Tohru Kozasa
Format: Article
Language:English
Published: MDPI AG 2011-03-01
Series:Pharmaceuticals
Subjects:
soft X-ray laser
soft X-ray microscopy
lipid raft
FRET
GPCR
drug discovery
Online Access:http://www.mdpi.com/1424-8247/4/3/524/

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