Pathological issues in biopsy specimens of men with prostate cancer eligible for active surveillance

Active surveillance (AS) is an important management option for men with lowrisk, clinically localized prostate cancer. The clinical parameters for patient selection and definition of progression for AS protocols are evolving as data from several large cohorts become mature. Vital to this process is...

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Main Authors: Roberta Mazzucchelli, Andrea Benedetto Galosi, Antonio Lopez-Beltran, Marina Scarpelli, Liang Cheng, Rodolfo Montironi
Format: Article
Language:English
Published: PAGEPress Publications 2014-12-01
Series:Archivio Italiano di Urologia e Andrologia
Subjects:
Online Access:http://www.pagepressjournals.org/index.php/aiua/article/view/5041
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spelling doaj-abc84c5c819e483d9a19a7beb77df3ba2020-11-25T01:25:21ZengPAGEPress PublicationsArchivio Italiano di Urologia e Andrologia1124-35622282-41972014-12-0186431431810.4081/aiua.2014.4.3144171Pathological issues in biopsy specimens of men with prostate cancer eligible for active surveillanceRoberta Mazzucchelli0Andrea Benedetto Galosi1Antonio Lopez-Beltran2Marina Scarpelli3Liang Cheng4Rodolfo Montironi5Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, AnconaDivision of Urology, “Augusto Murri” General Hospital, ASUR Marche, FermoDepartment of Surgery, Cordoba University Medical School, CordobaSection of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, AnconaDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, INSection of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, AnconaActive surveillance (AS) is an important management option for men with lowrisk, clinically localized prostate cancer. The clinical parameters for patient selection and definition of progression for AS protocols are evolving as data from several large cohorts become mature. Vital to this process is the critical role pathologic parameters play in identifying appropriate candidates for AS. These findings need to be reproducible and accurately reported by pathologists. Repeated biopsy after initial diagnosis of prostate cancer is recommended before inclusion in active surveillance for early detection of significant cancer.http://www.pagepressjournals.org/index.php/aiua/article/view/5041Prostate cancerProstate biopsyActive surveillanceTumour extentImmunohistochemistry
collection DOAJ
language English
format Article
sources DOAJ
author Roberta Mazzucchelli
Andrea Benedetto Galosi
Antonio Lopez-Beltran
Marina Scarpelli
Liang Cheng
Rodolfo Montironi
spellingShingle Roberta Mazzucchelli
Andrea Benedetto Galosi
Antonio Lopez-Beltran
Marina Scarpelli
Liang Cheng
Rodolfo Montironi
Pathological issues in biopsy specimens of men with prostate cancer eligible for active surveillance
Archivio Italiano di Urologia e Andrologia
Prostate cancer
Prostate biopsy
Active surveillance
Tumour extent
Immunohistochemistry
author_facet Roberta Mazzucchelli
Andrea Benedetto Galosi
Antonio Lopez-Beltran
Marina Scarpelli
Liang Cheng
Rodolfo Montironi
author_sort Roberta Mazzucchelli
title Pathological issues in biopsy specimens of men with prostate cancer eligible for active surveillance
title_short Pathological issues in biopsy specimens of men with prostate cancer eligible for active surveillance
title_full Pathological issues in biopsy specimens of men with prostate cancer eligible for active surveillance
title_fullStr Pathological issues in biopsy specimens of men with prostate cancer eligible for active surveillance
title_full_unstemmed Pathological issues in biopsy specimens of men with prostate cancer eligible for active surveillance
title_sort pathological issues in biopsy specimens of men with prostate cancer eligible for active surveillance
publisher PAGEPress Publications
series Archivio Italiano di Urologia e Andrologia
issn 1124-3562
2282-4197
publishDate 2014-12-01
description Active surveillance (AS) is an important management option for men with lowrisk, clinically localized prostate cancer. The clinical parameters for patient selection and definition of progression for AS protocols are evolving as data from several large cohorts become mature. Vital to this process is the critical role pathologic parameters play in identifying appropriate candidates for AS. These findings need to be reproducible and accurately reported by pathologists. Repeated biopsy after initial diagnosis of prostate cancer is recommended before inclusion in active surveillance for early detection of significant cancer.
topic Prostate cancer
Prostate biopsy
Active surveillance
Tumour extent
Immunohistochemistry
url http://www.pagepressjournals.org/index.php/aiua/article/view/5041
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