Helicobacter pylori Affects the Antigen Presentation Activity of Macrophages Modulating the Expression of the Immune Receptor CD300E through miR-4270

Helicobacter pylori Affects the Antigen Presentation Activity of Macrophages Modulating the Expression of the Immune Receptor CD300E through miR-4270

Helicobacter pylori (Hp) is a Gram-negative bacterium that infects the human gastric mucosa, leading to chronic inflammation. If not eradicated with antibiotic treatment, the bacterium persists in the human stomach for decades increasing the risk to develop chronic gastritis, gastroduodenal ulcer, a...

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Bibliographic Details
Main Authors: Matteo Pagliari, Fabio Munari, Marta Toffoletto, Silvia Lonardi, Francesco Chemello, Gaia Codolo, Caterina Millino, Chiara Della Bella, Beniamina Pacchioni, William Vermi, Matteo Fassan, Marina de Bernard, Stefano Cagnin
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
Helicobacter pylori
chronic inflammation
macrophages
microRNAs
CD300E
major histocompatibility complex class II
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01288/full

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