Inhibitory Effects of Compounds and Extracts from Ampelopsis brevipedunculata on IL-6-Induced STAT3 Activation

Inhibitory Effects of Compounds and Extracts from Ampelopsis brevipedunculata on IL-6-Induced STAT3 Activation

Ampelopsis brevipedunculata (Maxim.) Trautv. (AB), a traditional East Asian medicine, exhibits protective effects against several inflammatory diseases. Our search for an inhibitor of IL-6-induced JAK2/STAT3 activation revealed that AB ethanolic extract (ABE) had a significant inhibitory effect on I...

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Bibliographic Details
Main Authors:	Hyun-Jae Jang, Seung-Jae Lee, Hyung-Jin Lim, Kyungsook Jung, Soyoung Lee, Chan Sun Park, Seung Woong Lee, Mun-Chual Rho
Format:	Article
Language:	English
Published:	Hindawi Limited 2018-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2018/3684845

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