SR-BI Mediated Transcytosis of HDL in Brain Microvascular Endothelial Cells Is Independent of Caveolin, Clathrin, and PDZK1

SR-BI Mediated Transcytosis of HDL in Brain Microvascular Endothelial Cells Is Independent of Caveolin, Clathrin, and PDZK1

The vascular endothelium supplying the brain exhibits very low paracellular and transcellular permeability and is a major constituent of the blood-brain barrier. High-density lipoprotein (HDL) crosses the blood-brain barrier by transcytosis, but technical limitations have made it difficult to elucid...

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Bibliographic Details
Main Authors:	Karen Y. Fung, Changsen Wang, Steffen Nyegaard, Bryan Heit, Gregory D. Fairn, Warren L. Lee
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-10-01
Series:	Frontiers in Physiology
Subjects:	HDL transcytosis Blood-brain barrier Endothelial cells SR-BI Endocytosis Endothelial nitric oxide synthase
Online Access:	http://journal.frontiersin.org/article/10.3389/fphys.2017.00841/full

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