Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues

Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues

Background: Increasing evidence indicates that secretion of high mobility group box 1 protein (HMGB-1) is functionally associated with tendinopathy development. However, the underlying effect and mechanism of extracellular HMGB-1 on tendon cells are unclear. Methods: We tested the effect of exogenou...

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Bibliographic Details
Main Authors:	Chuanxin Zhang, Xinfeng Gu, Guangyi Zhao, Wang Wang, Jiahua Shao, Jun Zhu, Ting Yuan, Jiuyi Sun, Daibang Nie, Yiqin Zhou
Format:	Article
Language:	English
Published:	SAGE Publishing 2020-09-01
Series:	Therapeutic Advances in Chronic Disease
Online Access:	https://doi.org/10.1177/2040622320956429

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