Lentivirus-mediated Persephin over-expression in Parkinson′s disease rats

Lentivirus-mediated Persephin over-expression in Parkinson′s disease rats

Persephin, together with glial cell line-derived neurotrophic factor and neurturin, has a neurotrophic effect and promotes the survival of motor neurons cultured in vitro. In this study, dopaminergic neurons in the substantia nigra of rats were transfected with the Persephin gene. One week later 6-h...

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Bibliographic Details
Main Authors: Xiao-feng Yin, Hua-min Xu, Yun-xia Jiang, Yun-lai Zhi, Yu-xiu Liu, Heng-wei Xiang, Kai Liu, Xiao-dong Ding, Peng Sun
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; Persephin; lentivirus; Parkinson′s disease; dopaminergic neurons; gene therapy; over-expression; transfection; striatum; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=11;spage=1814;epage=1818;aulast=Yin

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