Spatiotemporal dynamics of early DNA damage response proteins on complex DNA lesions.

Spatiotemporal dynamics of early DNA damage response proteins on complex DNA lesions.

The response of cells to ionizing radiation-induced DNA double-strand breaks (DSB) is determined by the activation of multiple pathways aimed at repairing the injury and maintaining genomic integrity. Densely ionizing radiation induces complex damage consisting of different types of DNA lesions in c...

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Bibliographic Details
Main Authors: Frank Tobias, Daniel Löb, Nicor Lengert, Marco Durante, Barbara Drossel, Gisela Taucher-Scholz, Burkhard Jakob
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3582506?pdf=render

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