Case Report: Exertional rhabdomyolysis in a spin class participant with sickle cell trait [version 2; peer review: 2 approved]

• Main Authors: Teresa Longo, Matthew Shaines
• Format: Article
• Language: English
• Published: F1000 Research Ltd 2019-07-01
• Series: F1000Research
• Online Access: https://f1000research.com/articles/7-1742/v2

Exertional rhabdomyolysis is more common in sickle trait due to a predisposition to dehydration and inability to concentrate the urine. Spinning, an indoor cycling workout, has been associated with exertional rhabdomyolysis in recent reports. A consequence of rhabdomyolysis is acute kidney injury, which may be expected to be more common in patients with sickle trait. We report a case of spinning induced rhabdomyolysis in a woman with sickle trait that did not result in renal injury. “Spin rhabdo” is thought to be more severe than other causes of exertional rhabdomyolysis and is associated with higher creatine kinase levels than other causes of exertional rhabdomyolysis. Therefore, individuals with known sickle trait should consider visiting their physician prior to participation in spin classes for the first time. We might also consider voluntary screening for sickle trait in at risk populations prior to enrolling in spin classes given that many patients are unaware of their sickle trait status.