When Research Meets Reality–-Lessons Learned from a Pragmatic Multisite Group-Randomized Clinical Trial on Psychosocial Interventions in the Psychiatric and Addiction Field

When Research Meets Reality–-Lessons Learned from a Pragmatic Multisite Group-Randomized Clinical Trial on Psychosocial Interventions in the Psychiatric and Addiction Field

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Research on treatments for patients with co-occurring psychiatric and substance use disorders is of core importance and at the same time highly challenging as it includes patients that are normally excluded from clinical studies. Such research may require methodological adaptations which in turn cre...

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Main Authors: Linda E. Wüsthoff, Helge Waal, Rolf W. Gråwe
Format: Article
Language:English
Published: SAGE Publishing 2012-01-01
Series:Substance Abuse: Research and Treatment
Online Access:https://doi.org/10.4137/SART.S9245
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spelling doaj-ab77f37feb0b4e3eaa331cc3cea2fee92021-04-02T10:51:59ZengSAGE PublishingSubstance Abuse: Research and Treatment1178-22182012-01-01610.4137/SART.S9245When Research Meets Reality–-Lessons Learned from a Pragmatic Multisite Group-Randomized Clinical Trial on Psychosocial Interventions in the Psychiatric and Addiction FieldLinda E. Wüsthoff0Helge Waal1Rolf W. Gråwe2Norwegian Center for Addiction Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.Norwegian Center for Addiction Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.Department of Research and Development at the Alcohol and Drug Treatment Health Trust in Central Norway, Trondheim, Norway.Research on treatments for patients with co-occurring psychiatric and substance use disorders is of core importance and at the same time highly challenging as it includes patients that are normally excluded from clinical studies. Such research may require methodological adaptations which in turn create new challenges. However, the challenges that arise in such studies are insufficiently discussed in the literature. The aim of this methodology paper is, firstly, to discuss the methodological adaptations that may be required in such research; secondly, to describe how such adaptations created new challenges in a group-randomized clinical trial on Integrated Treatment amongst patients with co-occurring psychiatric and substance use disorders. We also discuss how these challenges might be understood and highlight lessons for future research in this field. Trial registration : NCT00447733.https://doi.org/10.4137/SART.S9245
collection DOAJ
language English
format Article
sources DOAJ
author Linda E. Wüsthoff
Helge Waal
Rolf W. Gråwe
spellingShingle Linda E. Wüsthoff
Helge Waal
Rolf W. Gråwe
When Research Meets Reality–-Lessons Learned from a Pragmatic Multisite Group-Randomized Clinical Trial on Psychosocial Interventions in the Psychiatric and Addiction Field
Substance Abuse: Research and Treatment
author_facet Linda E. Wüsthoff
Helge Waal
Rolf W. Gråwe
author_sort Linda E. Wüsthoff
title When Research Meets Reality–-Lessons Learned from a Pragmatic Multisite Group-Randomized Clinical Trial on Psychosocial Interventions in the Psychiatric and Addiction Field
title_short When Research Meets Reality–-Lessons Learned from a Pragmatic Multisite Group-Randomized Clinical Trial on Psychosocial Interventions in the Psychiatric and Addiction Field
title_full When Research Meets Reality–-Lessons Learned from a Pragmatic Multisite Group-Randomized Clinical Trial on Psychosocial Interventions in the Psychiatric and Addiction Field
title_fullStr When Research Meets Reality–-Lessons Learned from a Pragmatic Multisite Group-Randomized Clinical Trial on Psychosocial Interventions in the Psychiatric and Addiction Field
title_full_unstemmed When Research Meets Reality–-Lessons Learned from a Pragmatic Multisite Group-Randomized Clinical Trial on Psychosocial Interventions in the Psychiatric and Addiction Field
title_sort when research meets reality–-lessons learned from a pragmatic multisite group-randomized clinical trial on psychosocial interventions in the psychiatric and addiction field
publisher SAGE Publishing
series Substance Abuse: Research and Treatment
issn 1178-2218
publishDate 2012-01-01
description Research on treatments for patients with co-occurring psychiatric and substance use disorders is of core importance and at the same time highly challenging as it includes patients that are normally excluded from clinical studies. Such research may require methodological adaptations which in turn create new challenges. However, the challenges that arise in such studies are insufficiently discussed in the literature. The aim of this methodology paper is, firstly, to discuss the methodological adaptations that may be required in such research; secondly, to describe how such adaptations created new challenges in a group-randomized clinical trial on Integrated Treatment amongst patients with co-occurring psychiatric and substance use disorders. We also discuss how these challenges might be understood and highlight lessons for future research in this field. Trial registration : NCT00447733.
url https://doi.org/10.4137/SART.S9245
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