Combinatorial complexity and compositional drift in protein interaction networks.

The assembly of molecular machines and transient signaling complexes does not typically occur under circumstances in which the appropriate proteins are isolated from all others present in the cell. Rather, assembly must proceed in the context of large-scale protein-protein interaction (PPI) networks...

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Bibliographic Details
Main Authors: Eric J Deeds, Jean Krivine, Jérôme Feret, Vincent Danos, Walter Fontana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3297590?pdf=render

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