Label-Free Monitoring of Histone Acetylation Using Aptamer-Functionalized Field-Effect Transistor and Quartz Crystal Microbalance Sensors

Label-Free Monitoring of Histone Acetylation Using Aptamer-Functionalized Field-Effect Transistor and Quartz Crystal Microbalance Sensors

Chemical and enzymatic modifications of amino acid residues in protein after translation contain rich information about physiological conditions and diseases. Histone acetylation/deacetylation is the essential post-translational modification by regulating gene transcription. Such qualitative changes...

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Bibliographic Details
Main Authors: Tatsuro Goda, Yuji Miyahara
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Micromachines
Subjects:
post-translational modification
DNA aptamer
self-assembled monolayers
protein adsorption
potentiometry
cyclic voltammetry
Online Access:https://www.mdpi.com/2072-666X/11/9/820

Internet

https://www.mdpi.com/2072-666X/11/9/820

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