Propionate Protects against Lipopolysaccharide-Induced Mastitis in Mice by Restoring Blood–Milk Barrier Disruption and Suppressing Inflammatory Response

Propionate Protects against Lipopolysaccharide-Induced Mastitis in Mice by Restoring Blood–Milk Barrier Disruption and Suppressing Inflammatory Response

Mastitis, an inflammation of the mammary glands, is a major disease affecting dairy animal worldwide. Propionate is one of the main short-chain fatty acid that can exert multiple effects on the inflammatory process. The purpose of this study is to investigate the mechanisms underlying the protective...

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Bibliographic Details
Main Authors: Jingjing Wang, Zhengkai Wei, Xu Zhang, Yanan Wang, Zhengtao Yang, Yunhe Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
mastitis
sodium propionate
blood–milk barrier
NF-κB
histone deacetylases
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01108/full

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