Acute Nicotine Induces Anxiety and Disrupts Temporal Pattern Organization of Rat Exploratory Behavior in Hole-Board: A Potential Role for the Lateral Habenula

AbstractNicotine is one of the most addictive drugs of abuse. Tobacco smoking is a major cause of many health problems, and is the first preventable cause of death worldwide. Several findings show that nicotine exerts significant aversive as well as the well-known rewarding motivational effects. Les...

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Bibliographic Details
Main Authors: Maurizio eCasarrubea, Caitlin eDavies, Fabiana eFaulisi, Massimo ePierucci, Roberto eColangeli, Lucy ePartdrige, Stephanie eChambers, Daniel eCassar, Mario eValentino, Richard eMuscat, Arcangelo eBenigno, Giuseppe eCrescimanno, Giuseppe eDi Giovanni
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00197/full