Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy

<p>Abstract</p> <p>Background</p> <p>Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have been developed for predicting potential effects of amino acid substit...

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Bibliographic Details
Main Authors: Chen Ting, Sun Fengzhu, Yang Hua, Jiang Rui
Format: Article
Language:English
Published: BMC 2006-09-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/7/417