Reduced signal for polygenic adaptation of height in UK Biobank

Reduced signal for polygenic adaptation of height in UK Biobank

Several recent papers have reported strong signals of selection on European polygenic height scores. These analyses used height effect estimates from the GIANT consortium and replication studies. Here, we describe a new analysis based on the the UK Biobank (UKB), a large, independent dataset. We fin...

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Bibliographic Details
Main Authors: Jeremy J Berg, Arbel Harpak, Nasa Sinnott-Armstrong, Anja Moltke Joergensen, Hakhamanesh Mostafavi, Yair Field, Evan August Boyle, Xinjun Zhang, Fernando Racimo, Jonathan K Pritchard, Graham Coop
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-03-01
Series:eLife
Subjects:
polygenic adaptation
population genetics
quantitative genetics
natural selection
population structure
GWAS
Online Access:https://elifesciences.org/articles/39725

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