In vivo expression of peptidylarginine deiminase in Drosophila melanogaster.

In vivo expression of peptidylarginine deiminase in Drosophila melanogaster.

Peptidylarginine deiminase (PAD) modifies peptidylarginine and converts it to peptidylcitrulline in the presence of elevated calcium. Protein modification can lead to severe changes in protein structure and function, and aberrant PAD activity is linked to human pathologies. While PAD homologs have b...

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Bibliographic Details
Main Authors: Olena Mahneva, Monica G Risley, Ciny John, Sarah L Milton, Ken Dawson-Scully, William W Ja
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0227822

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