Characterization of a novel Nav1.5 channel mutation, A551T, associated with Brugada syndrome

Characterization of a novel Nav1.5 channel mutation, A551T, associated with Brugada syndrome

<p>Abstract</p> <p>Brugada syndrome is a life-threatening, inherited arrhythmia disorder associated with autosomal dominant mutations in SCN5A, the gene encoding the human cardiac Na<sup>+ </sup>channel α subunit (Nav1.5). Here, we characterized the biophysical properti...

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Bibliographic Details
Main Authors: Lai Ling-Ping, Chiang Kun-Chi, Shieh Ru-Chi
Format: Article
Language:English
Published: BMC 2009-08-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/16/1/76

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