Characterization of a novel Nav1.5 channel mutation, A551T, associated with Brugada syndrome
<p>Abstract</p> <p>Brugada syndrome is a life-threatening, inherited arrhythmia disorder associated with autosomal dominant mutations in SCN5A, the gene encoding the human cardiac Na<sup>+ </sup>channel α subunit (Nav1.5). Here, we characterized the biophysical properti...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-08-01
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| Series: | Journal of Biomedical Science |
| Online Access: | http://www.jbiomedsci.com/content/16/1/76 |