A higher concentration of an antigen within the nucleolus may prevent its proper recognition by specific antibodies

Transient transfection of HeLa cells with a plasmid encoding the full-length human fibrillarin fused to a green fluorescent protein (GFP) resulted in two major patterns of intensity of the nucleolar labeling for the chimeric protein: weak and strong. Both patterns were maintained in fibrillarin-GFP...

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Bibliographic Details
Main Authors: EV Sheval, MA Polzikov, MOJ Olson, OV Zatsepina
Format: Article
Language:English
Published: PAGEPress Publications 2009-06-01
Series:European Journal of Histochemistry
Online Access:https://www.ejh.it/index.php/ejh/article/view/935