Effects of Fat and Sugar, Either Consumed or Infused toward the Brain, on Hypothalamic ER Stress Markers

Effects of Fat and Sugar, Either Consumed or Infused toward the Brain, on Hypothalamic ER Stress Markers

Protein-folding stress at the Endoplasmic Reticulum (ER) occurs in the hypothalamus during diet-induced obesity (DIO) and is linked to metabolic disease development. ER stress is buffered by the activation of the unfolded protein response (UPR), a controlled network of pathways inducing a set of gen...

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Bibliographic Details
Main Authors: Evita Belegri, Merel Rijnsburger, Leslie Eggels, Unga Unmehopa, Wiep Scheper, Anita Boelen, Susanne E. la Fleur
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Neuroscience
Subjects:
ER stress response
hypothalamus
food restriction
fatty acids
sugar
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00270/full

Internet

http://journal.frontiersin.org/article/10.3389/fnins.2017.00270/full

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