Lysophosphatidic Acid Upregulates Recepteur D’origine Nantais Expression and Cell Invasion via Egr-1, AP-1, and NF-κB Signaling in Bladder Carcinoma Cells

Lysophosphatidic Acid Upregulates Recepteur D’origine Nantais Expression and Cell Invasion via Egr-1, AP-1, and NF-κB Signaling in Bladder Carcinoma Cells

Muscle invasive bladder carcinoma is a highly malignant cancer with a high mortality rate, due to its tendency to metastasize. The tyrosine kinase recepteur d’origine nantais (RON) promotes bladder carcinoma metastasis. Lysophosphatidic acid (LPA) is a phospholipid derivative, which acts a...

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Bibliographic Details
Main Authors: Pham Ngoc Khoi, Shinan Li, Ung Trong Thuan, Dhiraj Kumar Sah, Taek Won Kang, Thi Thinh Nguyen, Sen Lian, Yong Xia, Young Do Jung
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
lysophosphatidic acid
recepteur d’origine nantais
bladder cancer
egr-1
ap-1
nf-κb
Online Access:https://www.mdpi.com/1422-0067/21/1/304

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