Safety and efficacy of the 10-day melarsoprol schedule for the treatment of second stage Rhodesiense sleeping sickness.

Safety and efficacy of the 10-day melarsoprol schedule for the treatment of second stage Rhodesiense sleeping sickness.

OBJECTIVE: Assessment of the safety and efficacy of a 10-day melarsoprol schedule in second stage T.b. rhodesiense patients and the effect of suramin-pretreatment on the incidence of encephalopathic syndrome (ES) during melarsoprol therapy. DESIGN: Sequential conduct of a proof-of-concept trial (n =...

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Bibliographic Details
Main Authors: Irene Kuepfer, Caecilia Schmid, Mpairwe Allan, Andrew Edielu, Emma P Haary, Abbas Kakembo, Stafford Kibona, Johannes Blum, Christian Burri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3435133?pdf=render

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