General Method for the Preparation of Substituted 2-Amino-4H,5H-pyrano[4,3-b]pyran-5-ones and 2-Amino-4H-pyrano[3,2-c]pyridine-5-ones

General Method for the Preparation of Substituted 2-Amino-4H,5H-pyrano[4,3-b]pyran-5-ones and 2-Amino-4H-pyrano[3,2-c]pyridine-5-ones

Reaction of 4-hydroxy-6-methyl-2-pyrone (1a) as well as 4-hydroxy-6-methyl-2(1H)-pyridones (1b-d) with arylmethylene malononitriles or arylmethylene methyl cyanoacetates (2a-h) leads to the formation of the very stable 5,6-fused bicyclic 2-amino-4Hpyran derivatives 3a-3af.

Bibliographic Details
Main Authors:	Dieter Heber, Ivo C. Ivanov, Edmont V. Stoyanov
Format:	Article
Language:	English
Published:	MDPI AG 2000-01-01
Series:	Molecules
Subjects:	pyrano[4 3-b]pyran pyrano[3 2-c]pyridine arylmethylene malononitrile arylmethylene cyanoacetate Michael addition
Online Access:	http://www.mdpi.com/1420-3049/5/1/19/

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