MICA-129 Dimorphism and Soluble MICA Are Associated With the Progression of Multiple Myeloma

MICA-129 Dimorphism and Soluble MICA Are Associated With the Progression of Multiple Myeloma

Natural killer (NK) cells are immune innate effectors playing a pivotal role in the immunosurveillance of multiple myeloma (MM) since they are able to directly recognize and kill MM cells. In this regard, among activating receptors expressed by NK cells, NKG2D represents an important receptor for th...

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Bibliographic Details
Main Authors: Alessandra Zingoni, Elisabetta Vulpis, Francesca Cecere, Maria G. Amendola, Daniel Fuerst, Taron Saribekyan, Adnane Achour, Tatyana Sandalova, Ilaria Nardone, Agnese Peri, Alessandra Soriani, Cinzia Fionda, Elena Mariggiò, Maria T. Petrucci, Maria R. Ricciardi, Joannis Mytilineos, Marco Cippitelli, Cristina Cerboni, Angela Santoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
multiple myeloma
natural killer cells
NKG2D receptor
MICA polymorphism
predictive biomarker
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00926/full

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