Erwin Schroedinger, Francis Crick and epigenetic stability

<p>Abstract</p> <p>Schroedinger's book 'What is Life?' is widely credited for having played a crucial role in development of molecular and cellular biology. My essay revisits the issues raised by this book from the modern perspective of epigenetics and systems biolog...

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Main Author: Ogryzko Vasily V
Format: Article
Language:English
Published: BMC 2008-04-01
Series:Biology Direct
Online Access:http://www.biology-direct.com/content/3/1/15
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spelling doaj-ab1509b0e54c40dd8ba978f07b5e65802020-11-24T22:59:02ZengBMCBiology Direct1745-61502008-04-01311510.1186/1745-6150-3-15Erwin Schroedinger, Francis Crick and epigenetic stabilityOgryzko Vasily V<p>Abstract</p> <p>Schroedinger's book 'What is Life?' is widely credited for having played a crucial role in development of molecular and cellular biology. My essay revisits the issues raised by this book from the modern perspective of epigenetics and systems biology. I contrast two classes of potential mechanisms of epigenetic stability: 'epigenetic templating' and 'systems biology' approaches, and consider them from the point of view expressed by Schroedinger. I also discuss how quantum entanglement, a nonclassical feature of quantum mechanics, can help to address the 'problem of small numbers' that led Schroedinger to promote the idea of a molecular code-script for explaining the stability of biological order.</p> http://www.biology-direct.com/content/3/1/15
collection DOAJ
language English
format Article
sources DOAJ
author Ogryzko Vasily V
spellingShingle Ogryzko Vasily V
Erwin Schroedinger, Francis Crick and epigenetic stability
Biology Direct
author_facet Ogryzko Vasily V
author_sort Ogryzko Vasily V
title Erwin Schroedinger, Francis Crick and epigenetic stability
title_short Erwin Schroedinger, Francis Crick and epigenetic stability
title_full Erwin Schroedinger, Francis Crick and epigenetic stability
title_fullStr Erwin Schroedinger, Francis Crick and epigenetic stability
title_full_unstemmed Erwin Schroedinger, Francis Crick and epigenetic stability
title_sort erwin schroedinger, francis crick and epigenetic stability
publisher BMC
series Biology Direct
issn 1745-6150
publishDate 2008-04-01
description <p>Abstract</p> <p>Schroedinger's book 'What is Life?' is widely credited for having played a crucial role in development of molecular and cellular biology. My essay revisits the issues raised by this book from the modern perspective of epigenetics and systems biology. I contrast two classes of potential mechanisms of epigenetic stability: 'epigenetic templating' and 'systems biology' approaches, and consider them from the point of view expressed by Schroedinger. I also discuss how quantum entanglement, a nonclassical feature of quantum mechanics, can help to address the 'problem of small numbers' that led Schroedinger to promote the idea of a molecular code-script for explaining the stability of biological order.</p>
url http://www.biology-direct.com/content/3/1/15
work_keys_str_mv AT ogryzkovasilyv erwinschroedingerfranciscrickandepigeneticstability
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