Propentofylline reduces glial scar development following gliotoxic damage in the rat brainstem
ABSTRACT Propentofylline is a xanthine derivative that depresses activation of glial cells, whose responses contribute to neural tissue damage during inflammation. Ethidium bromide injection into the central nervous system induces local oligodendroglial and astrocytic loss, resulting in primary demy...
Main Authors: | Eduardo Fernandes Bondan, Maria de Fátima Monteiro Martins, Pietro Domingues Dossa, Lígia Bocamino Viebig, Carolina Vieira Cardoso, João Lopes Martins Júnior, Maria Martha Bernardi |
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Format: | Article |
Language: | English |
Published: |
Academia Brasileira de Neurologia (ABNEURO)
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Series: | Arquivos de Neuro-Psiquiatria |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016000900730&lng=en&tlng=en |
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