Genistein inhibits AOM/DSS-induced colon cancer by regulating lipid droplet accumulation and the SIRT1/FOXO3a pathway in high-fat diet-fed female mice

Obesity is one of the risk factors associated with colon cancer. In this study, we investigated the effect of genistein on colon cancer in obese mice and its underlying mechanism. Colon cancer was induced by azoxymethane/dextran sulfate sodium injection in Kun Ming mice, and they were fed with regul...

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Bibliographic Details
Main Authors: Wentao Qi, Yong Wang, Jinli Yao, Hui Sun, Xiaoliang Duan, Ge Song, Shaojie Pang, Chunling Wang, Aike Li
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Food and Agricultural Immunology
Subjects:
Online Access:http://dx.doi.org/10.1080/09540105.2019.1684452