Preliminary analyses of scRNA sequencing and immunohistochemistry of children's lung tissues indicate the expression of SARS‐CoV‐2 entry‐related genes may not be the key reason for the milder syndromes of COVID‐19 in children
Main Authors: | , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2021-05-01
|
Series: | Clinical and Translational Medicine |
Online Access: | https://doi.org/10.1002/ctm2.300 |
id |
doaj-ab0b3f2ff3424dbd8ac39ce624f1f28e |
---|---|
record_format |
Article |
spelling |
doaj-ab0b3f2ff3424dbd8ac39ce624f1f28e2021-05-28T10:14:30ZengWileyClinical and Translational Medicine2001-13262021-05-01115n/an/a10.1002/ctm2.300Preliminary analyses of scRNA sequencing and immunohistochemistry of children's lung tissues indicate the expression of SARS‐CoV‐2 entry‐related genes may not be the key reason for the milder syndromes of COVID‐19 in childrenYue Tao0Ruwen Yang1Chen Wen2Jue Fan3Jing Ma4Qiao He5Zhiguang Zhao6Xinyu Song7Hao Chen8Guocheng Shi9Minzhi Yin10Nan Fang11Hao Zhang12Huiwen Chen13Xi Mo14The Laboratory of Pediatric Infectious Diseases, Pediatric Translational Medicine Institute Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University Shanghai ChinaThe Laboratory of Pediatric Infectious Diseases, Pediatric Translational Medicine Institute Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University Shanghai ChinaDepartment of Cardiothoracic Surgery Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University Shanghai ChinaSingleron Biotechnologies Nanjing ChinaDepartment of Pathology Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University Shanghai ChinaDepartment of Pathology Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University Shanghai ChinaWenzhou Medical University Second Affiliated Hospital Wenzhou ChinaDepartment of Cardiothoracic Surgery First Affiliated Hospital of Soochow University Suzhou ChinaDepartment of Cardiothoracic Surgery Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University Shanghai ChinaDepartment of Cardiothoracic Surgery Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University Shanghai ChinaDepartment of Pathology Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University Shanghai ChinaSingleron Biotechnologies Nanjing ChinaDepartment of Cardiothoracic Surgery Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University Shanghai ChinaDepartment of Cardiothoracic Surgery Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University Shanghai ChinaThe Laboratory of Pediatric Infectious Diseases, Pediatric Translational Medicine Institute Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University Shanghai Chinahttps://doi.org/10.1002/ctm2.300 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yue Tao Ruwen Yang Chen Wen Jue Fan Jing Ma Qiao He Zhiguang Zhao Xinyu Song Hao Chen Guocheng Shi Minzhi Yin Nan Fang Hao Zhang Huiwen Chen Xi Mo |
spellingShingle |
Yue Tao Ruwen Yang Chen Wen Jue Fan Jing Ma Qiao He Zhiguang Zhao Xinyu Song Hao Chen Guocheng Shi Minzhi Yin Nan Fang Hao Zhang Huiwen Chen Xi Mo Preliminary analyses of scRNA sequencing and immunohistochemistry of children's lung tissues indicate the expression of SARS‐CoV‐2 entry‐related genes may not be the key reason for the milder syndromes of COVID‐19 in children Clinical and Translational Medicine |
author_facet |
Yue Tao Ruwen Yang Chen Wen Jue Fan Jing Ma Qiao He Zhiguang Zhao Xinyu Song Hao Chen Guocheng Shi Minzhi Yin Nan Fang Hao Zhang Huiwen Chen Xi Mo |
author_sort |
Yue Tao |
title |
Preliminary analyses of scRNA sequencing and immunohistochemistry of children's lung tissues indicate the expression of SARS‐CoV‐2 entry‐related genes may not be the key reason for the milder syndromes of COVID‐19 in children |
title_short |
Preliminary analyses of scRNA sequencing and immunohistochemistry of children's lung tissues indicate the expression of SARS‐CoV‐2 entry‐related genes may not be the key reason for the milder syndromes of COVID‐19 in children |
title_full |
Preliminary analyses of scRNA sequencing and immunohistochemistry of children's lung tissues indicate the expression of SARS‐CoV‐2 entry‐related genes may not be the key reason for the milder syndromes of COVID‐19 in children |
title_fullStr |
Preliminary analyses of scRNA sequencing and immunohistochemistry of children's lung tissues indicate the expression of SARS‐CoV‐2 entry‐related genes may not be the key reason for the milder syndromes of COVID‐19 in children |
title_full_unstemmed |
Preliminary analyses of scRNA sequencing and immunohistochemistry of children's lung tissues indicate the expression of SARS‐CoV‐2 entry‐related genes may not be the key reason for the milder syndromes of COVID‐19 in children |
title_sort |
preliminary analyses of scrna sequencing and immunohistochemistry of children's lung tissues indicate the expression of sars‐cov‐2 entry‐related genes may not be the key reason for the milder syndromes of covid‐19 in children |
publisher |
Wiley |
series |
Clinical and Translational Medicine |
issn |
2001-1326 |
publishDate |
2021-05-01 |
url |
https://doi.org/10.1002/ctm2.300 |
work_keys_str_mv |
AT yuetao preliminaryanalysesofscrnasequencingandimmunohistochemistryofchildrenslungtissuesindicatetheexpressionofsarscov2entryrelatedgenesmaynotbethekeyreasonforthemildersyndromesofcovid19inchildren AT ruwenyang preliminaryanalysesofscrnasequencingandimmunohistochemistryofchildrenslungtissuesindicatetheexpressionofsarscov2entryrelatedgenesmaynotbethekeyreasonforthemildersyndromesofcovid19inchildren AT chenwen preliminaryanalysesofscrnasequencingandimmunohistochemistryofchildrenslungtissuesindicatetheexpressionofsarscov2entryrelatedgenesmaynotbethekeyreasonforthemildersyndromesofcovid19inchildren AT juefan preliminaryanalysesofscrnasequencingandimmunohistochemistryofchildrenslungtissuesindicatetheexpressionofsarscov2entryrelatedgenesmaynotbethekeyreasonforthemildersyndromesofcovid19inchildren AT jingma preliminaryanalysesofscrnasequencingandimmunohistochemistryofchildrenslungtissuesindicatetheexpressionofsarscov2entryrelatedgenesmaynotbethekeyreasonforthemildersyndromesofcovid19inchildren AT qiaohe preliminaryanalysesofscrnasequencingandimmunohistochemistryofchildrenslungtissuesindicatetheexpressionofsarscov2entryrelatedgenesmaynotbethekeyreasonforthemildersyndromesofcovid19inchildren AT zhiguangzhao preliminaryanalysesofscrnasequencingandimmunohistochemistryofchildrenslungtissuesindicatetheexpressionofsarscov2entryrelatedgenesmaynotbethekeyreasonforthemildersyndromesofcovid19inchildren AT xinyusong preliminaryanalysesofscrnasequencingandimmunohistochemistryofchildrenslungtissuesindicatetheexpressionofsarscov2entryrelatedgenesmaynotbethekeyreasonforthemildersyndromesofcovid19inchildren AT haochen preliminaryanalysesofscrnasequencingandimmunohistochemistryofchildrenslungtissuesindicatetheexpressionofsarscov2entryrelatedgenesmaynotbethekeyreasonforthemildersyndromesofcovid19inchildren AT guochengshi preliminaryanalysesofscrnasequencingandimmunohistochemistryofchildrenslungtissuesindicatetheexpressionofsarscov2entryrelatedgenesmaynotbethekeyreasonforthemildersyndromesofcovid19inchildren AT minzhiyin preliminaryanalysesofscrnasequencingandimmunohistochemistryofchildrenslungtissuesindicatetheexpressionofsarscov2entryrelatedgenesmaynotbethekeyreasonforthemildersyndromesofcovid19inchildren AT nanfang preliminaryanalysesofscrnasequencingandimmunohistochemistryofchildrenslungtissuesindicatetheexpressionofsarscov2entryrelatedgenesmaynotbethekeyreasonforthemildersyndromesofcovid19inchildren AT haozhang preliminaryanalysesofscrnasequencingandimmunohistochemistryofchildrenslungtissuesindicatetheexpressionofsarscov2entryrelatedgenesmaynotbethekeyreasonforthemildersyndromesofcovid19inchildren AT huiwenchen preliminaryanalysesofscrnasequencingandimmunohistochemistryofchildrenslungtissuesindicatetheexpressionofsarscov2entryrelatedgenesmaynotbethekeyreasonforthemildersyndromesofcovid19inchildren AT ximo preliminaryanalysesofscrnasequencingandimmunohistochemistryofchildrenslungtissuesindicatetheexpressionofsarscov2entryrelatedgenesmaynotbethekeyreasonforthemildersyndromesofcovid19inchildren |
_version_ |
1721424248957829120 |