MagFRET: the first genetically encoded fluorescent Mg2+ sensor.

Magnesium has important structural, catalytic and signaling roles in cells, yet few tools exist to image this metal ion in real time and at subcellular resolution. Here we report the first genetically encoded sensor for Mg(2+), MagFRET-1. This sensor is based on the high-affinity Mg(2+) binding doma...

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Bibliographic Details
Main Authors: Laurens H Lindenburg, Jan L Vinkenborg, Jorn Oortwijn, Stijn J A Aper, Maarten Merkx
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3846734?pdf=render