| Summary: | The objective. To conduct a comparative assessment of circulation different genotypes of group A rotaviruses on the territory of the Orenburg region during several epidemic seasons. Materials and methods. The article presents the findings of genotyping faeces of 182 patients with rotavirus infection. The patient’s age was below 5 years. The methods of ELISA, PCR were used. Results. 10 genotypes of group A rotaviruses circulated during 3 epidemic seasons in the Orenburg region, the dominant genotypes were G4[P]8, G3[P]8, G2[P]4. The greatest variety of the circulating genotypes of group A rotaviruses were noted among children aged below two years. Genotype G4[P]8 was presented as the most frequently occurring in all age categories. 20 (11%) of the samples with the simultaneous combination of different genotypes of rotaviruses (Mixt) form were revealed. Conclusion. The dominant genotype variants were singled out and their regional variety were shown in the different epidemic seasons. The characteristic of rotavirus genotype among children in various age was defined. The activity of the circulation of rotaviruses in the region was evaluated.
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