The Role of chk2 in Response to DNA Damage in Cancer Cells

The Role of chk2 in Response to DNA Damage in Cancer Cells

Accumulation of gene changes and chromosomal instability in response to cellular DNA damage lead to cancer. DNA damage induces cell cycle checkpoints pathways. Checkpoints regulate DNA replication and cell cycle progression, chromatin restructuring, and apoptosis. Checkpoint kinase 2 (chk2) is activ...

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Bibliographic Details
Main Author:	Fereshteh Mir Mohammadrezaei
Format:	Article
Language:	English
Published:	University of Mazandaran 2015-03-01
Series:	Journal of Genetic Resources
Subjects:	keywords: chk2 dna damage cancer cell therapy apoptosis
Online Access:	http://sc.journals.umz.ac.ir/article_1115_2ac642bab3bc57fdfbee0371c0d9960b.pdf

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