MegaLMM: Mega-scale linear mixed models for genomic predictions with thousands of traits

Abstract Large-scale phenotype data can enhance the power of genomic prediction in plant and animal breeding, as well as human genetics. However, the statistical foundation of multi-trait genomic prediction is based on the multivariate linear mixed effect model, a tool notorious for its fragility wh...

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Bibliographic Details
Main Authors: Daniel E. Runcie, Jiayi Qu, Hao Cheng, Lorin Crawford
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-021-02416-w

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