A ssDNA Aptamer That Blocks the Function of the Anti-FLAG M2 Antibody

A ssDNA Aptamer That Blocks the Function of the Anti-FLAG M2 Antibody

Using SELEX (systematic evolution of ligands by exponential enrichment), we serendipitously discovered a ssDNA aptamer that binds selectively to the anti-FLAG M2 antibody. The aptamer consisted of two motifs (CCTTA and TGTCTWCC) separated by 2-3 bases, and the elimination of one or the other motif a...

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Bibliographic Details
Main Authors:	Amanda S. Lakamp, Michel M. Ouellette
Format:	Article
Language:	English
Published:	Hindawi Limited 2011-01-01
Series:	Journal of Nucleic Acids
Online Access:	http://dx.doi.org/10.4061/2011/720798

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