Further development of mathematical description for combined toxicity: A case study of lead–fluoride combination

Further development of mathematical description for combined toxicity: A case study of lead–fluoride combination

In this article, we check and develop further some postulates of the theory and mathematical modeling of combined toxic effect that we proposed earlier [1]. To this end, we have analyzed the results of an experiment on rats exposed during 6 weeks to repeated intraperitoneal injections of lead acetat...

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Bibliographic Details
Main Authors: Vladimir G. Panov, Boris A. Katsnelson, Anatoly N. Varaksin, Larisa I. Privalova, Ekaterina P. Kireyeva, Marina P. Sutunkova, Irene E. Valamina, Olga Yu. Beresneva
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Toxicology Reports
Subjects:
Combined toxicity
Lead
Fluoride
Response surface
Zero interaction
Isobole
Unidirectional and opposing action of toxicants
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750015000219

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http://www.sciencedirect.com/science/article/pii/S2214750015000219

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