Detection of CRISPR-Cas9-Mediated Mutations Using a Carbon Nanotube-Modified Electrochemical Genosensor

Detection of CRISPR-Cas9-Mediated Mutations Using a Carbon Nanotube-Modified Electrochemical Genosensor

The CRISPR-Cas9 system has facilitated the genetic modification of various model organisms and cell lines. The outcomes of any CRISPR-Cas9 assay should be investigated to ensure/improve the precision of genome engineering. In this study, carbon nanotube-modified disposable pencil graphite electrodes...

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Bibliographic Details
Main Authors: Ezgi Kivrak, Tekle Pauzaite, Nikki A. Copeland, John G. Hardy, Pinar Kara, Melike Firlak, Atike I. Yardimci, Selahattin Yilmaz, Fahreddin Palaz, Mehmet Ozsoz
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biosensors
Subjects:
CRISPR-Cas9
homology-directed repair (HDR)
electrochemical genosensor
mutation detection
carbon nanotube-modified PGE
Online Access:https://www.mdpi.com/2079-6374/11/1/17

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