[18F]DPA-714: direct comparison with [11C]PK11195 in a model of cerebral ischemia in rats.

<h4>Purpose</h4>Neuroinflammation is involved in several brain disorders and can be monitored through expression of the translocator protein 18 kDa (TSPO) on activated microglia. In recent years, several new PET radioligands for TSPO have been evaluated in disease models. [(18)F]DPA-714...

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Main Authors: Hervé Boutin, Christian Prenant, Renaud Maroy, James Galea, Andrew D Greenhalgh, Alison Smigova, Christopher Cawthorne, Peter Julyan, Shane M Wilkinson, Samuel D Banister, Gavin Brown, Karl Herholz, Michael Kassiou, Nancy J Rothwell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23418569/pdf/?tool=EBI