Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date
Wimolsiri Iamsumang, Kanchana Leerunyakul, Poonkiat Suchonwanit Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Poonkiat Suchonwanit Email poonkiat@hotmail.comAbstract: The currently approved treatment f...
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doaj-aa6b4e2ec9ac4edb8bb12027579f18f12020-11-25T02:35:13ZengDove Medical PressDrug Design, Development and Therapy1177-88812020-03-01Volume 1495195952200Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to DateIamsumang WLeerunyakul KSuchonwanit PWimolsiri Iamsumang, Kanchana Leerunyakul, Poonkiat Suchonwanit Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Poonkiat Suchonwanit Email poonkiat@hotmail.comAbstract: The currently approved treatment for female pattern hair loss (FPHL) includes topical minoxidil administration; however, this treatment fails to achieve hair regrowth in some patients. Finasteride, a selective 5α-reductase inhibitor (5-ARI), may be considered as an alternative treatment. However, because of its potential teratogenic effects, clinical studies and use of finasteride for FPHL are limited. In this review, we aim to summarize the literature regarding the pharmacology, clinical efficacy, and adverse effects of oral finasteride for the treatment of FPHL and to provide novel therapeutic options including topical finasteride and dutasteride, a new generation 5-ARI, for the treatment of FPHL.Keywords: alopecia, androgenetic alopecia, dutasteride, hair loss, topical finasteride, therapyhttps://www.dovepress.com/finasteride-and-its-potential-for-the-treatment-of-female-pattern-hair-peer-reviewed-article-DDDTalopeciaandrogenetic alopeciadutasteridehair losstopical finasteridetherapy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Iamsumang W Leerunyakul K Suchonwanit P |
spellingShingle |
Iamsumang W Leerunyakul K Suchonwanit P Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date Drug Design, Development and Therapy alopecia androgenetic alopecia dutasteride hair loss topical finasteride therapy |
author_facet |
Iamsumang W Leerunyakul K Suchonwanit P |
author_sort |
Iamsumang W |
title |
Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date |
title_short |
Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date |
title_full |
Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date |
title_fullStr |
Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date |
title_full_unstemmed |
Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date |
title_sort |
finasteride and its potential for the treatment of female pattern hair loss: evidence to date |
publisher |
Dove Medical Press |
series |
Drug Design, Development and Therapy |
issn |
1177-8881 |
publishDate |
2020-03-01 |
description |
Wimolsiri Iamsumang, Kanchana Leerunyakul, Poonkiat Suchonwanit Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Poonkiat Suchonwanit Email poonkiat@hotmail.comAbstract: The currently approved treatment for female pattern hair loss (FPHL) includes topical minoxidil administration; however, this treatment fails to achieve hair regrowth in some patients. Finasteride, a selective 5α-reductase inhibitor (5-ARI), may be considered as an alternative treatment. However, because of its potential teratogenic effects, clinical studies and use of finasteride for FPHL are limited. In this review, we aim to summarize the literature regarding the pharmacology, clinical efficacy, and adverse effects of oral finasteride for the treatment of FPHL and to provide novel therapeutic options including topical finasteride and dutasteride, a new generation 5-ARI, for the treatment of FPHL.Keywords: alopecia, androgenetic alopecia, dutasteride, hair loss, topical finasteride, therapy |
topic |
alopecia androgenetic alopecia dutasteride hair loss topical finasteride therapy |
url |
https://www.dovepress.com/finasteride-and-its-potential-for-the-treatment-of-female-pattern-hair-peer-reviewed-article-DDDT |
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