A new method of N to C sequential ligation using thioacid capture ligation and native chemical ligation

Sequential peptide ligation strategy becomes more and more important in large protein or long peptides chemical synthesis due to the limited peptide/protein size obtained by solid phase synthesis of individual peptides or even one-step peptide ligation. Herein, we developed an alternative method whi...

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Bibliographic Details
Main Authors: Wen Hou, Lei Liu, Xiaohong Zhang, Chuanfa Liu
Format: Article
Language:English
Published: The Royal Society 2018-01-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.172455