Mice Expressing a "Hyper-Sensitive" Form of the Cannabinoid Receptor 1 (CB1) Are Neither Obese Nor Diabetic.

Mice Expressing a "Hyper-Sensitive" Form of the Cannabinoid Receptor 1 (CB1) Are Neither Obese Nor Diabetic.

Multiple lines of evidence implicate the endocannabinoid signaling system in the modulation of metabolic disease. Genetic or pharmacological inactivation of CB1 in rodents leads to reduced body weight, resistance to diet-induced obesity, decreased intake of highly palatable food, and increased energ...

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Bibliographic Details
Main Authors: David J Marcus, Michael L Zee, Brian J Davis, Chris P Haskins, Mary-Jeanette Andrews, Randa Amin, Angela N Henderson-Redmond, Ken Mackie, Traci A Czyzyk, Daniel J Morgan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4976987?pdf=render

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http://europepmc.org/articles/PMC4976987?pdf=render

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