From individual to collective 3D cancer dissemination: roles of collagen concentration and TGF-β

Abstract Cancer cells have the ability to migrate from the primary (original) site to other places in the body. The extracellular matrix affects cancer cell migratory capacity and has been correlated with tissue-specific spreading patterns. However, how the matrix orchestrates these behaviors remain...

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Bibliographic Details
Main Authors: J. Plou, Y. Juste-Lanas, V. Olivares, C. del Amo, C. Borau, J. M. García-Aznar
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-30683-4