Immobilization of Bone Morphogenetic Protein on DOPA- or Dopamine-Treated Titanium Surfaces to Enhance Osseointegration
Titanium was treated with 3,4-dihydroxy-L-phenylalanine (DOPA) or dopamine to immobilize bone morphogenetic protein-2 (BMP2), a biomolecule. DOPA and dopamine solutions turned into suspensions, and precipitates were produced at high pH. Both treatments produced a brown surface on titanium that was t...
Main Authors: | Jeonghwa Kang, Seiichi Tada, Takashi Kitajima, Tae Il Son, Toshiro Aigaki, Yoshihiro Ito |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2013-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2013/265980 |
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