Human sperm chromatin epigenetic potential: genomics, proteomics, and male infertility

Human sperm chromatin epigenetic potential: genomics, proteomics, and male infertility

The classical idea about the function of the mammalian sperm chromatin is that it serves to transmit a highly protected and transcriptionally inactive paternal genome, largely condensed by protamines, to the next generation. In addition, recent sperm chromatin genome-wide dissection studies indicate...

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Bibliographic Details
Main Authors: Judit Castillo, Josep Maria Estanyol, Josep Lluis Ballescà, Rafael Oliva
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Asian Journal of Andrology
Subjects:
gene regulation
Musashi
Musashi-1
Musashi-2
posttranscriptional control
RNA binding proteins
spermatogenesis
splicing
testis
translation
cell fate
cell stress
importin
karyopherin
nucleocytoplasmic transport
spermatid
spermatocyte
artificial insemination
biomarker
fertility
fertilization
flow cytometry
infertility
nanotechnology
oocyte activation
Postacrosomal Sheath WWI Domain Binding Protein
sperm
SPTRX3
thioredoxin
ubiquitin
ATP binding cassette transporters
albumin
high-density lipoprotein
lipid rafts
membrane fluidity
membrane microdomains
membrane packing
oxysterols
reverse cholesterol transport
sterol transporters
egg
heat shock protein A2
molecular chaperone
sperm-egg interactions
dehydrogenases
oxidases
peroxiredoxins
reactive oxygen species
spermatozoa
thiols
thioredoxins
antigen-presenting cells
autoimmunity
dendritic cells
epididymis
macrophages
peripheral tolerance
sperm maturation
genomics
male infertility
proteomics
sperm chromatin
sperm epigenetics
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2015;volume=17;issue=4;spage=601;epage=609;aulast=Castillo

Internet

http://www.ajandrology.com/article.asp?issn=1008-682X;year=2015;volume=17;issue=4;spage=601;epage=609;aulast=Castillo

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