Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis

Abstract Background Tumor-associated macrophages (TAMs) are major components of tumor microenvironment that frequently associated with tumor metastasis in human cancers. Circulating tumor cell (CTC), originating from primary tumor sites, is considered to be the precursors of tumor metastasis. Howeve...

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Bibliographic Details
Main Authors: Chen Wei, Chaogang Yang, Shuyi Wang, Dongdong Shi, Chunxiao Zhang, Xiaobin Lin, Qing Liu, Rongzhang Dou, Bin Xiong
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Molecular Cancer
Subjects:
EMT
Online Access:http://link.springer.com/article/10.1186/s12943-019-0976-4