Interaction of Signaling Lymphocytic Activation Molecule Family 1 (SLAMF1) receptor with Trypanosoma cruzi is strain-dependent and affects NADPH oxidase expression and activity.

The receptor Signaling Lymphocyte-Activation Molecule Family 1 (SLAMF1) controls susceptibility to Infection by the lethal Trypanosoma cruzi Y strain. To elucidate whether genetic diversity of the parasite was related with disease susceptibility, we further analyzed the role of SLAMF1 using 6 differ...

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Bibliographic Details
Main Authors: Cristina Poveda, Alfonso Herreros-Cabello, Francisco Callejas-Hernández, Jesús Osuna-Pérez, María C Maza, Carlos Chillón-Marinas, Jossela Calderón, Konstantinos Stamatakis, Manuel Fresno, Núria Gironès
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008608