Association of endothelial and glycocalyx injury biomarkers with fluid administration, development of acute kidney injury, and 90-day mortality: data from the FINNAKI observational study

Association of endothelial and glycocalyx injury biomarkers with fluid administration, development of acute kidney injury, and 90-day mortality: data from the FINNAKI observational study

Abstract Background Injury to endothelium and glycocalyx predisposes to vascular leak, which may subsequently lead to increased fluid requirements and worse outcomes. In this post hoc study of the prospective multicenter observational Finnish Acute Kidney Injury (FINNAKI) cohort study conducted in 1...

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Bibliographic Details
Main Authors: Nina Inkinen, Ville Pettilä, Päivi Lakkisto, Anne Kuitunen, Sakari Jukarainen, Stepani Bendel, Outi Inkinen, Tero Ala-Kokko, Suvi T. Vaara, the FINNAKI Study Group
Format: Article
Language:English
Published: SpringerOpen 2019-09-01
Series:Annals of Intensive Care
Subjects:
Biomarker
Glycocalyx
Sepsis
Fluid balance
Fluid resuscitation
Soluble thrombomodulin
Online Access:http://link.springer.com/article/10.1186/s13613-019-0575-y

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